ACTIVE INGREDIENT
Each tablet contains:Oxandrolone 10 mg
DESCRIPTION
Oxandrolone is a synthetic anabolic steroid, structurally similar to testosterone. It is primarily used to promote weight gain in patients recovering from surgery, severe trauma, or chronic infections. Additionally, it helps mitigate muscle loss associated with prolonged corticosteroid use and alleviates bone pain in individuals with osteoporosis. Known for its strong anabolic properties and relatively mild androgenic effects, Oxandrolone is often favored in both medical and athletic settings.
PHARMACOLOGICAL PROPERTIES
Mechanism of Action:
Oxandrolone acts as an agonist at androgen receptors, stimulating protein synthesis and promoting muscle growth while enhancing nitrogen retention.
Pharmacokinetics:
- Absorption: Rapidly absorbed after oral administration.
- Distribution: Widely distributed in body tissues.
- Metabolism: Primarily metabolized in the liver.
- Half-life: Approximately 9 hours in the second phase.
- Excretion: Eliminated mainly through urine.
INDICATIONS
Oxandrolone is indicated for:
- Weight gain: Following extensive surgery, severe trauma, or chronic infections.
- Muscle preservation: In patients undergoing long-term corticosteroid therapy.
- Bone pain relief: Associated with osteoporosis.
- Developmental support: In girls with Turner syndrome.
DOSAGE AND ADMINISTRATION
Dosage:
- Usual Adult Dose for Weight Loss: 2.5 mg to 20 mg orally in 2 to 4 divided doses over 2 to 4 weeks.
- Usual Geriatric Dose for Weight Loss: 5 mg orally twice a day.
- Usual Pediatric Dose for Weight Loss: Up to 0.1 mg per kg of body weight, repeated intermittently as needed.
Administration:
Take the medication by mouth as directed by a healthcare provider, with or without food.
CONTRAINDICATIONS
- Hypersensitivity to Oxandrolone or any formulation component.
- Pregnancy and lactation (Pregnancy Category X).
- Active breast cancer in females or prostate cancer in males.
- Severe liver disease or hypercalcemia.
WARNINGS AND PRECAUTIONS
- Hepatic Effects: Risk of liver toxicity; monitor liver function regularly.
- Cardiovascular Risks: Potential for increased cholesterol levels and cardiovascular complications; regular monitoring is recommended.
- Androgenic Effects: Possible side effects include acne, hair loss, and virilization in women; caution is advised for female patients.
- Fluid Retention: May cause edema, increasing the risk of heart failure; monitor for symptoms such as shortness of breath or rapid weight gain.
ADVERSE REACTIONS
Common Adverse Reactions:
- Acne
- Oily skin
- Hair loss
- Mood changes
Serious Adverse Reactions:
- Liver problems: Symptoms may include jaundice and abdominal pain.
- Cardiovascular issues: Increased risk of heart attack or stroke.
- Hormonal imbalances: Gynecomastia in men, virilization symptoms in women.
INTERACTIONS
- Anticoagulants: May enhance anticoagulant effects, increasing bleeding risk; monitor coagulation parameters closely.
- Corticosteroids: Concurrent use may increase the risk of fluid retention and electrolyte disturbances.
USE IN SPECIFIC POPULATIONS
- Pregnancy and Lactation: Contraindicated due to potential teratogenic effects.
- Pediatric Use: Not recommended due to risks of growth interference.
- Geriatric Use: Caution advised due to increased risk of adverse effects related to cardiovascular health and liver function.
OVERDOSAGE
There is no specific antidote for Oxandrolone overdose. Supportive care and symptomatic treatment are recommended while monitoring liver and cardiovascular function closely.
STORAGE
Store below 25°C (77°F). Protect from light. Keep out of reach of children.
PACKAGING
Oxandrolone 10 mg is supplied as oral tablets in various packaging configurations.
MANUFACTURER
Oxydine Metabolics Switzerland
Oxydine.org
Hi@Oxydine.org

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