Anadrol 50 mg

ACTIVE INGREDIENT

Each tablet contains:Oxymetholone 50 mg

DESCRIPTION

Oxymetholone, marketed under the brand name Anadrol-50, is a potent anabolic steroid that mimics testosterone. It is primarily used to treat specific types of anemia, particularly those caused by bone marrow failure. Oxymetholone is known for its strong anabolic effects, which promote significant muscle mass gains and improve red blood cell production. Despite its medical uses, it is often misused in athletic circles for performance enhancement.

PHARMACOLOGICAL PROPERTIES

Mechanism of Action:
Oxymetholone functions as an agonist at androgen receptors, enhancing protein synthesis and nitrogen retention, which are crucial for muscle growth.Pharmacokinetics:

• Absorption: Rapidly absorbed after oral administration.
• Distribution: Widely distributed in body tissues.
• Metabolism: Primarily metabolized in the liver.
• Half-life: Approximately 8 to 9 hours.
• Excretion: Eliminated mainly through urine.

INDICATIONS

Oxymetholone is indicated for:

• Anemia treatment: Particularly in cases of aplastic anemia and myelofibrosis.
• Weight gain: In patients recovering from surgery or severe trauma.
• Muscle wasting: Associated with chronic infections or corticosteroid use.

DOSAGE AND ADMINISTRATION

Dosage:

• Usual Adult Dose for Anemia: 1 to 5 mg/kg orally per day, typically starting at 1 to 2 mg/kg/day. Treatment duration may last from three to six months.
• Usual Pediatric Dose for Anemia: Same as adults, individualized based on weight.

Administration:
Take the medication orally with or without food, following the prescribed dosage instructions.

CONTRAINDICATIONS

• Hypersensitivity to oxymetholone or any formulation component.
• Pregnancy and lactation (Pregnancy Category X).
• Active breast cancer in females or prostate cancer in males.
• Severe liver dysfunction or nephrotic syndrome.

WARNINGS AND PRECAUTIONS

1. Hepatic Effects: Risk of hepatotoxicity; regular liver function monitoring is recommended.
2. Cardiovascular Risks: Potential for increased cholesterol levels and cardiovascular complications; monitor lipid profiles regularly.
3. Androgenic Effects: Possible side effects include acne, hair loss, and virilization in women; caution is advised for female patients.
4. Fluid Retention: May cause edema; monitor for symptoms such as rapid weight gain or shortness of breath.

ADVERSE REACTIONS

Common Adverse Reactions:

• Acne
• Mood changes
• Insomnia
• Swelling

Serious Adverse Reactions:

• Liver damage: Symptoms may include jaundice and abdominal pain.
• Cardiovascular issues: Increased risk of heart attack or stroke.
• Hormonal imbalances: Gynecomastia in men and virilization symptoms in women.

INTERACTIONS

1. Anticoagulants: May enhance anticoagulant effects, increasing bleeding risk; monitor coagulation parameters closely.
2. Corticosteroids: Concurrent use may increase fluid retention risk.

USE IN SPECIFIC POPULATIONS

• Pregnancy and Lactation: Contraindicated due to potential teratogenic effects.
• Pediatric Use: Not recommended due to risks of growth interference and hormonal imbalance.
• Geriatric Use: Caution advised due to increased risk of adverse effects related to cardiovascular health and liver function.

OVERDOSAGE

There is no specific antidote for oxymetholone overdose. Supportive care and symptomatic treatment are recommended while monitoring liver and cardiovascular function closely.

STORAGE

Store below 25°C (77°F). Protect from light. Keep out of reach of children.

PACKAGING

Oxymetholone 50 mg is supplied as oral tablets in various packaging configurations.

MANUFACTURER

Oxydine Metabolics Switzerland

Oxydine.org
Hi@Oxydine.org